Niels C. Pedersen, DVM PhD, Distinguished Professor Emeritus Center for Companion Animal Health School of Veterinary Medicine, UC Davis We use the same criteria for monitoring treatment as described in the JFMS field trial paper. Owners are asked to keep track of temperature, weight, activity, appetite, clinical signs of original Read more…
Background– Feline leukemia virus (FeLV) is a retrovirus related to murine leukemia virus that has existed among feral cats for tens of thousands of years before its discovery in 1964 (Jarrett, et al., 1964). FeLV infection occurs mainly among cats under 3-8 years of age (reviewed Pedersen, 1998, 1991). The Read more…
Niels C. Pedersen, DVM PhD June 1, 2021 Introduction – Neurological involvement occurs in about 5-10% of FIP cases. This may vary between regions, as Turkish street cats appear to have a greater incidence based on this author’s experiences. The age of onset parallels that of other forms of FIP, with Read more…
Introduction – Pregnancy is an interesting immunologic paradox. Although organs and tissues from individuals of same (allograft) or different species (xenograft) are recognized as foreign and destroyed, the fetus, which is an allograft, is not. Prevention of fetal rejection is accompanied by events linked to the complex hormonal changes that are Read more…
Niels C. Pedersen, DVM PhD April 6, 2021 The use of supplements for dogs and cats has become increasingly more common, mirroring the increase in the use of supplements for people. I have also noticed that many owners of cats are using numerous supplements to augment treatment GS-441524 treatment for Read more…
February 11, 2021 Background: The relationship of age and FIP incidence has been well discussed in the literature and has even been the topic of research [1]. Twenty-nine percent of FIP cases occurs in kittens under 0.5 years of age, 50% under 1.0 years, 80% less than 3.0 years, and Read more…
Updated January 23, 2021 Treatment with oral formulations of GS-441524 By Nicole Jacque, Niels C. Pedersen The initial field testing of GS-441524 for FIP treatment involved subcutaneous injection. This route of administration was based on prior pharmacokinetic (PK) studies done on laboratory cats. Intravenous and subcutaneous routes of injection yielded Read more…
This last year has been a milestone in our fight against FIP. We extended our landmark studies of 2018, when we published on a collaborative study with colleagues at Kansas State University on a drug called GC376. This was the first drug to successfully cure cats of FIP. In this Read more…
Dr. Pedersen has updated information about FIP in the “About FIP” category. Three additional articles entitled FIP Treatment, Black-Market Production and Sale of GS-441524 and GC376 and Neurological and ocular FIP have also been included in this same category. To the numerous owners of cats with FIP that contact us Read more…
September 9, 2019 Dear owner of a cat with FIP: I am receiving many emails and phone calls regarding cats that are either being treated with GS-441524 with or without help from veterinarians or from owners that intend to start treatment with GS from Chinese black-market sources and need advice. Read more…